Publications by authors named "K M Zackowski"
Introduction: The cerebellum is a common lesion site in persons with multiple sclerosis (PwMS). Physiologic and anatomic studies have identified a topographic organization of the cerebellum including functionally distinct motor and cognitive areas. This study implemented a recent parcellation algorithm developed by Han et al.
View Article and Find Full Text PDFThe body of research on exercise and physical activity among persons with multiple sclerosis(MS) has expanded rapidly in quantity, but not necessarily quality, over the past 20+ years. There is evidence for beneficial effects of exercise and physical activity on immune cells and neurotrophic factors, brain structure and function, walking and cognitive performance, fatigue, depression, and pain, and quality of life among persons with MS. Nevertheless, there is heterogeneity in the outcomes of exercise and physical activity, and a recognition of substantial challenges for improving the effectiveness of those behaviors in MS.
View Article and Find Full Text PDFArticle Synopsis
- A prodrome refers to the early signs or symptoms of a disease that appear before the main symptoms emerge, and is recognized in various conditions like Parkinson's and type 1 diabetes.
- Recent findings suggest that multiple sclerosis (MS) also has a prodromal stage, which presents an opportunity for early intervention to potentially prevent or delay the onset of classical MS.
- There is still much to learn about the prodromal stage of MS, so more research is necessary to establish clear criteria for identifying individuals at high risk for developing MS, which could aid in future treatment trials.