The Impact of Public Health and Social Measures (PHSMs) on SARS-CoV-2 Transmission in the WHO European Region (2020-2022).

Background: Between 2020 and 2022, countries used a range of different public health and social measures (PHSMs) to reduce the transmission of SARS-CoV-2. The impact of these PHSMs varied as the pandemic progressed, variants of concern (VOCs) emerged, vaccines rolled out and acceptance/uptake rates evolved. In this study, we assessed the impact of PHSMs in the World Health Organization (WHO) European Region during VOC phases.

Clinician Perspectives on the Management of Hearing Loss in Patients With Limited English Proficiency.

Objective: Clinicians face challenges in managing the growing population of patients with limited English proficiency (LEP) and hearing loss (HL) in the United States. This study seeks to investigate provider perspectives on evaluating, counseling, and treating HL in LEP patients.

Study Design: Prospective descriptive study.

An Integration of Theory, Practice, and Research in Critical Gerontological Social Work: An Interview with Professor Deborah O'Connor.

This article is an interview with Professor Deborah O'Connor, a Canadian and internationally well-known scholar in gerontological social work, by her doctoral student Karen Wong before Professor O'Connor's retirement. The interview aims to honor Professor O'Connor's scholarship and contribution to research, practice, policy, and education and to inspire junior researchers and trainees, educators and students, and practitioners in gerontological social work. Professor O'Connor's ground-breaking scholarship is marked by understanding aging and dementia from critical perspectives.

Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models.

KRAS is the most frequently mutated oncogene in lung adenocarcinoma, with G12C and G12V being the most predominant forms. Recent breakthroughs in KRASG12C inhibitors have transformed the clinical management of patients with G12C mutation and advanced our understanding of its function. However, little is known about the targeted disruption of KRASG12V, partly due to a lack of specific inhibitors.