Publications by authors named "K M Williamson"
Background: Households in areas of socio-economic deprivation are more likely to consume diets low in fruit and vegetables. Fresh Street is a place-based fruit and vegetable voucher scheme with vouchers redeemable with local independent (non-supermarket) vendors. Paper vouchers are offered to all households in a geographical area regardless of household type, size, or income with no requirement to demonstrate need.
View Article and Find Full Text PDFBackground: The win ratio (WR) is an emerging alternative for reporting composite outcomes, prioritizing clinically significant events such as mortality while incorporating surrogate measures. However, its benefits should be weighed against limitations, particularly the influence of lower hierarchical outcomes. This secondary analysis of the PARAGLIDE-HF trial performed a WR sensitivity analysis using a modified hierarchical composite outcome to assess the utility of WR sensitivity analysis and the efficacy of sacubitril/valsartan versus valsartan.
View Article and Find Full Text PDFMalaria control and elimination efforts would benefit from the identification and validation of new malaria chemotherapeutics. Recently, a transgenic line was used to perform a series of high-throughput in vitro screens for new antimalarials acting against the parasite sexual stages. The screens identified pyrimidine azepine chemotypes with potent activity.
View Article and Find Full Text PDFArticle Synopsis
- The study sought to identify specific genetic-respiratory disease interactions that increase the risk of developing rheumatoid arthritis (RA).
- Using case-control data from Mass General Brigham and the Mayo Clinic, researchers found significant associations between certain respiratory diseases and RA risk, with particular genetic factors influencing this relationship.
- The results suggest that understanding these genetic-respiratory interactions could lead to more personalized approaches for preventing, diagnosing, and treating RA in the future.
Purpose: The purpose of this quality improvement (QI) project was to establish and evaluate a process to improve use of positive airway pressure (PAP) therapy on the day of surgery, postoperative day 0 (POD 0), for Veterans using home PAP therapy for obstructive sleep apnea (OSA) admitted to the hospital after surgery.
Design: QI project using a preimplementation and postimplementation design.
Methods: The QI project occurred from June 2023 through November 2023.