Cannabinoid-2 Receptor Activation Attenuates Sulfur Mustard Analog 2-Chloroethyl-Ethyl-Sulfide-Induced Acute Lung Injury in Mice.

Exposure to sulfur mustard (SM; 2,2'-dichlorodiethyl sulfide) causes toxicity in the human body, particularly the lungs. The molecular mechanisms of SM-induced lung damage are elusive, and no effective treatments exist. This study explores the anti-inflammatory potential of cannabinoid receptor 2 (CB2R) activation in mitigating acute lung injury (ALI) and inflammation induced by 2-chloroethyl ethyl sulfide (CEES), a structural analog of SM.

Development of dual disease resistant Basmati rice varieties offer significant economic advantage and impetus to sustainable crop production.

Introduction: Bacterial blight and blast are the major diseases causing production losses to an extent of 31.52% to 67.79%, respectively.

Physiological and molecular investigations on a high-yielding variety and near-isogenic line of rice under continuous phosphorus stress reveal major regulatory function of Pup1 QTL.

Phosphorous (P) plays crucial roles in cellular functioning including respiration, photosynthesis, and membranes. P deficiency in the soil causes stunted growth, smaller/erect leaves, lesser tillers, and a considerable decrease in yield. To decipher the functions of Pup1 QTL and delineate the potential effects of continuous P stress on plant growth, yield/quality, physio-biochemical and molecular analyses of rice [Pusa-44 (P deficiency sensitive) and a near-isogenic line-23 (NIL-23), (harbouring Pup1 QTL, tolerant genotype)] were hydroponically grown under P continuous stress [deficiency (4 ppm) or extravagance (≥32 ppm)] till maturity.

Screening for hemoglobin disorders and investigating their hematological and demographic profile among patients attending a tertiary-care hospital in southern India-a descriptive study.

Background: Hemoglobinopathies and thalassemias are widely prevalent autosomal inherited recessive disorders of the structure and synthesis of hemoglobin, respectively. Given the regional heterogeneity of these disorders, this study was undertaken to elucidate the patterns and prevalence of these disorders from this region.

Methods: This was a tertiary-care hospital-based study in southern India over 4 years.