Publications by authors named "K M Thierfelder"
Article Synopsis
- Automated perfusion imaging can identify stroke patients eligible for thrombolysis, but it's not widely available; a new method using CT hypoperfusion-hypodensity mismatch offers a potential alternative.
- In a study involving 247 patients, 88.7% were deemed eligible for thrombolysis, with the hypoperfusion-hypodensity mismatch detecting 96.4% of eligible patients within the 4.5-hour time frame compared to only 44.7% by the automated method.
- This new CT method demonstrated higher sensitivity for identifying eligible patients but lower specificity, suggesting that it could help more patients receive treatment.
Background And Purpose: Many patients with stroke cannot receive intravenous thrombolysis because the time of symptom onset is unknown. We tested whether a simple method of computed tomography (CT)-based quantification of water uptake in the ischemic tissue can identify patients with stroke onset within 4.5 hours.
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- The study aimed to determine if CT hypoperfusion-hypodensity mismatch can effectively identify patients experiencing ischemic stroke within 4.5 hours of their symptoms starting.
- Out of 666 patients analyzed, a significant majority (94.2%) with symptom onset within 4.5 hours showed hypoperfusion-hypodensity mismatch, indicating strong predictive value for identifying timely thrombolysis candidates.
- The findings suggest that detecting this mismatch on CT scans can potentially guide treatment decisions for patients whose stroke onset time is unclear.
Background: Multiparametric magnetic resonance imaging (MRI) of the prostate plays a central role in the diagnosis of patients with suspected prostate cancer. The increasing distribution and application of the guideline for the standardization of image acquisition, evaluation, and reporting (Prostate Imaging - Reporting and Data System, PI-RADS), which was updated in 2019 to version 2.1, contributes to the success of the technique.
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- The study aimed to investigate the prevalence and clinical importance of extravascular findings (EVFs) on magnetic resonance angiography (MRA) in patients with suspected or known peripheral artery disease (PAD).
- The research involved re-evaluating MRAs of 194 patients, uncovering 501 EVFs in 172 patients, with 12% of those having major clinical relevance, mainly in soft tissues and linked to infections or neoplastic conditions.
- The findings highlight the need for thorough evaluation of all organ systems in MRA reports, as significant non-vascular issues can frequently arise alongside vascular assessments.