Publications by authors named "K M Shivakumar"

This paper demonstrates that ash composites, comprising fly ash and polyurethane, can be used to develop value-added products that exhibit an effective decrease in the leaching of coal ash inorganics to less than one-third of the Environmental Protection Agency (EPA)'s maximum contaminant level (MCL) when soaked in a water circulation system for 14 months. Furthermore, the composite blocks remain safe even with ruptured surfaces. The concept of encapsulating fly ash within ash composites by using a polar polymer to bind the fine inorganic particles, mimicking how nature does it in the original unburned coal, ensures the safety of the composite.

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Article Synopsis
  • * Researchers isolated and characterized EVs from various cell types (NSCs, MGE cells, and GABAergic interneurons) and loaded them with GABA to test their effectiveness in a rat model of epilepsy induced by kainic acid.
  • * Results indicated that GABA-encapsulated EVs significantly reduced the frequency and severity of seizures in treated rats, suggesting that this method could be a promising alternative for epilepsy management.
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Unlabelled: Background The I-LMA ventilates while providing a port for blind insertion of an endotracheal tube. The ILMA Fastrach is used especially for intubating in a difficult airway scenario. Its accompanying endotracheal tube is not economical nor readily available.

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() and () are two long noncoding RNAs upregulated in multiple cancers, marking these RNAs as therapeutic targets. While traditional small-molecule and antisense-based approaches are effective, we report a locked nucleic acid (LNA)-based approach that targets the and triple helices, structures comprised of a U-rich internal stem-loop and an A-rich tract. Two LNA oligonucleotides resembling the A-rich tract (i.

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