Publications by authors named "K M Purushotham"
Article Synopsis
- Long-term and chronic stress are significant contributors to depression, prompting research into the antidepressant effects of an ethanolic extract of flowers (ESAF) on stressed mice.
- The study involved administering ESAF to mice under various stress conditions over a week, using behavioral tests to measure antidepressant activity and assessing biochemical changes post-treatment.
- Results indicated that ESAF significantly reduced indicators of depression and improved antioxidant enzyme activity in the mice's hippocampus, suggesting its potential as a natural antidepressant through mechanisms involving oxidative stress reduction.
Single particle inductively coupled plasma-mass spectrometry (spICP-MS) is an emerging technique capable of simultaneously measuring nanoparticle size and number concentration of metal-containing nanoparticles (NPs) at environmental levels. single particle ICP-MS will become an established measurement method once the metrological quality of the measurement results it produces have been proven incontrovertibly. This Article presents the first validation of spICP-MS capabilities for measuring mean NP size and number size distribution of gold nanoparticles (AuNPs).
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- * Out of 40 tumors examined, survivin was detected in all, with significantly higher expression levels in malignant tumors (average value of 18.87) compared to benign ones (average value of 0.94).
- * The findings suggest that higher survivin levels correlate with lower survival rates and poorer prognosis in dogs with malignant tumors, especially those exceeding the median cutoff value of 3.74.
Background: Culicoides spp. biting midges transmit bluetongue virus (BTV), the aetiological agent of bluetongue (BT), an economically important disease of ruminants. In southern India, hyperendemic outbreaks of BT exert high cost to subsistence farmers in the region, impacting on sheep production.
View Article and Find Full Text PDFPresence of polyphenolic content in various part of the plant exhibit wide pharmacological activities including antioxidant activity. The present study was designed to evaluate the phenolic contents (total phenols, flavonoid and tannins) and antioxidant properties of ethanolic extracts of flower, leaf, pod, bark and root obtained from Cassia auriculata. Ethanolic extracts of various parts of C.
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