Publications by authors named "K M Naseem"
Granule secretion is an essential platelet function that contributes not only to haemostasis but also to wound healing, inflammation, and atherosclerosis. Granule secretion from platelets is facilitated, at least in part, by Soluble N-ethylmaleimide-Sensitive Factor (NSF) Attachment Protein Receptor (SNARE) complex-mediated granule fusion. Although α-synuclein is a protein known to modulate the assembly of the SNARE complex in other cells, its role in platelet function remains poorly understood.
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- Quantum dots (QDs) are small semiconductor particles that could improve biomedical imaging and drug delivery, with Indium phosphide QDs covered by zinc sulphide being a more biocompatible option.
- This study reveals that PEGylating these QDs significantly reduces platelet activation and aggregation, which is important to prevent excessive blood clotting.
- By decreasing the interaction between QDs and platelets, PEGylation enhances the safety and effectiveness of QDs for use in medical applications.
Introduction: This review article gives an overview of the biogenic synthesis of metal nanoparticles (mNPs) while using extract as a reducing and stabilizing agent. The subtropical fruit tree i.e lychee contains phytochemicals such as flavonoids, terpenoids, and polyphenolic compounds which act as reducing agents and convert the metal ions into metal atoms that coagulate to form mNPs.
View Article and Find Full Text PDFIncreasing energy demands and low-carbon emission energy carriers are global challenges for renewable energy resources. Regarding the aforementioned issues, magnesium-based composites are promising candidates for energy carriers. However, rapid initial hydrolysis kinetics and higher hydrogen yields are the objectives for practical applications.
View Article and Find Full Text PDFBackground: Infectious diseases are a major cause of mortality in spite of existing public health, anti-microbial and vaccine interventions. We aimed to define plasma proteomic associates of infection mortality and then apply Mendelian randomisation (MR) to yield biomarkers that may be causally associated.
Methods: We used UK Biobank plasma proteomic data to associate 2923 plasma proteins with infection mortality before 31st December 2019 (240 events in 52,520 participants).