The Functioning of Ethics Committees in Kazakhstan: Results and Recommendations.

Background: Sixteen RECs were randomly selected from various institutions across Kazakhstan, representing both public and private sectors and covering biomedical and socio-behavioral research reviews.

Objective: This research addresses a critical knowledge gap by providing empirical data on REC operations in Kazakhstan, facilitating a better understanding of how these committees align with international ethical standards and best practices. Furthermore, by situating our findings within the broader context of REC performance in LMICs, we aim to highlight specific challenges unique to Kazakhstan and propose evidence-based recommendations.

Diabetic Ketoacidosis Without Diabetes Mellitus in Acute Pancreatitis.

Background/objective: Diabetic ketoacidosis (DKA) is typically but not exclusively seen in patients with a history of diabetes mellitus.

Case Report: This is a case of 39 year-old male who was diagnosed with acute pancreatitis based on characteristic symptoms and positive CT findings on presentation. Laboratory testing revealed elevated serum glucose 251 mg/dL, low serum bicarbonate 8 mmol/L, increased anion gap 21, and elevated serum beta-hydroxybutyrate 9.

Drugs stimulating insulin secretion in early clinical development for the treatment of type 1 diabetes: what's new?

Introduction: Type 1 diabetes is a chronic autoimmune condition characterized by the selective destruction of insulin-producing beta cells in the pancreas. The etiology of T1D is multifactorial, with a combination of genetic susceptibility and environmental triggers believed to underlie beta-cell destruction. Preserving and prolonging beta-cell function in T1D is a pivotal therapeutic objective that can mitigate disease progression and improve glycemic control.

A novel meta learning based stacked approach for diagnosis of thyroid syndrome.

Thyroid syndrome, a complex endocrine disorder, involves the dysregulation of the thyroid gland, impacting vital physiological functions. Common causes include autoimmune disorders, iodine deficiency, and genetic predispositions. The effects of thyroid syndrome extend beyond the thyroid itself, affecting metabolism, energy levels, and overall well-being.