Publications by authors named "K M McEvoy"
Article Synopsis
- Premenstrual Disorders (PMDs), including PMS and PMDD, significantly affect women, and childhood trauma may increase the risk of experiencing these disorders and premenstrual exacerbation (PME).
- * This study analyzed data from 391 participants to explore the relationship between childhood trauma and various levels of premenstrual symptoms, comparing those with PMDs, PME, psychiatric controls, and healthy controls.
- * Results indicated that individuals with PME and psychiatric conditions reported more severe childhood trauma, with a correlation between trauma and premenstrual symptoms especially strong in the PMD group, highlighting the lasting impact of early trauma on mental health.
Gammaherpesviruses are oncogenic viruses that establish lifelong infections and are significant causes of morbidity and mortality. Vaccine strategies to limit gammaherpesvirus infection and disease are in development, but there are no FDA-approved vaccines for Epstein-Barr or Kaposi sarcoma herpesvirus. As a new approach to gammaherpesvirus vaccination, we developed and tested a replication-deficient virus (RDV) platform, using murine gammaherpesvirus 68 (MHV68), a well-established mouse model for gammaherpesvirus pathogenesis studies and preclinical therapeutic evaluations.
View Article and Find Full Text PDFSurgical outcomes of total duct excision in the diagnosis and management of nipple discharge.
Ann R Coll Surg Engl
July 2024
Introduction: Total duct excision (TDE) is performed for the diagnosis and management of nipple discharge. The Association of Breast Surgery's recent guidelines recommend considering diagnostic surgery for single-duct, blood-stained or clear nipple discharge, and for symptomatic management.
Methods: We retrospectively reviewed the diagnostic and surgical outcomes of all cases of TDE between January 2013 and November 2019.
Article Synopsis
- The initiative aimed to engage children affected by cancer, survivors, families, and healthcare professionals to identify and prioritize research questions that could shape future studies on childhood cancer.
- An online survey gathered over 1,200 potential questions, which were then refined and shortlisted through surveys and workshops with participants, resulting in a final consensus on the Top 10 priorities.
- The most significant concern identified was the need for more effective and less burdensome treatments for children with cancer, emphasizing a focus on improving patient care and outcomes.
Background: Previous priority setting exercises have sought to involve children, but in the final reporting, it is evident that few children had been engaged through the process. A primary aim in the Children's Cancer Priority Setting Partnership was to find out from children what they want research to focus on. We report on our experience to inform methods of engagement with children in future James Lind Alliance Priority Setting Partnerships and similar exercises.
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