Publications by authors named "K M Hager"
Introduction: Myeloid neoplasms (MNs) frequently harbor pathogenic mutations not detected by karyotyping and fluorescence in situ hybridization; hence, next-generation sequencing (NGS) is necessary for diagnosis, risk stratification, and therapy. If, however, NGS is not clinically indicated but still performed, the results may promote futile avenues of investigation, heighten patient distress, and increase cost.
Methods: We created criteria to approve NGS testing for MN (MN-NGS) with the goal of maximizing actionable results.
Article Synopsis
- Climate change is increasing the frequency of high temperatures, which poses serious health risks for patients with chronic diseases; empowering these patients is critical for their safety.
- This study investigates how light to moderate heat affects health complaints and explores links between self-reported protective behaviors and psychosocial factors.
- Conducted with 61 patients, the study collected data on their health complaints, protective behaviors, and chronic conditions, applying various statistical models to analyze the relationship between heat exposure and health outcomes.
TP53 mutations in patients with AML and MDS frequently portend a poor prognosis, related to both p53 allele status and blast count. In 2022, the ICC and WHO released updated guidelines for classifying p53-mutated AML/MDS. The characteristics of p53 mutations, their associated co-mutations, and their effects on overall survival (OS) are not known in the context of these new guidelines.
View Article and Find Full Text PDFis a bacterium commonly found in the oral cavities of cats and dogs. Infections are particularly common in immunocompromised patients who have been exposed to bites or come in contact with saliva from these animals. The manifestations of infection include bacteremia, fever, and, rarely, meningitis.
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