Publications by authors named "K M Elias"
Article Synopsis
- Forgiveness is when someone stops feeling angry or hurt about what someone else did to them, and this study looks at how people with HIV deal with forgiving the person they believe gave them the virus.
- The researchers talked to 14 people with HIV to understand how they feel about forgiveness and found three main ideas: anger can be damaging, forgiveness has a deeper meaning, and it takes time and steps to truly forgive.
- The study suggests that helping people with HIV learn more about forgiveness could be really important for their emotional health.
Article Synopsis
- Gestational trophoblastic neoplasia (GTN) is a group of curable pregnancy-related tumors, but 25% of patients may experience treatment-resistant or recurring cases after chemotherapy.
- The review highlights various factors affecting the prognosis of low-risk GTN, such as FIGO risk score, patient age, tumor characteristics, and hCG levels, emphasizing the need for personalized treatment approaches.
- It also identifies independent risk factors for resistance and recurrence, noting that previous studies have limitations like small sample sizes and lack of comprehensive analysis, which could impact the understanding of these issues.
Ultra high-risk gestational trophoblastic neoplasia (GTN) refers to patients with World Health Organization prognostic risk scores of at least 13. The mortality risk for these patients averages 30%. Ultra high-risk GTN more frequently presents with higher tumor volume, liver and/or brain metastases, and very high human chorionic gonadotropin levels.
View Article and Find Full Text PDFInitial Diagnosis and Treatment of Low-Risk Gestational Trophoblastic Neoplasia.
Hematol Oncol Clin North Am
December 2024
Gestational trophoblastic neoplasia (GTN) is a rare form of cancer that is treated according to the World Health Organization (WHO) risk score, which predicts responsiveness to single-agent chemotherapy. Patients with WHO risk scores ≤6 have low-risk GTN, for which cure rates near 100%. Most women with low-risk GTN will respond to single-agent chemotherapy, which is given with either methotrexate or dactinomycin, and allows women to retain their fertility.
View Article and Find Full Text PDFPlacental Site Trophoblastic Tumors and Epithelioid Trophoblastic Tumors.
Hematol Oncol Clin North Am
December 2024
Article Synopsis
- - Placental site trophoblastic disease (PSTT) and epithelioid trophoblastic tumor (ETT) are rare types of gestational trophoblastic neoplasia (GTN) that present distinct clinical features and treatment approaches, notably without significantly elevated human chorionic gonadotropin (hCG) levels.
- - Management typically involves surgery, such as hysterectomy, and lymph node removal; there are some cases where fertility-sparing surgeries have been performed for localized disease.
- - While early-stage, low-risk cases show good survival rates, high-risk patients, especially those with advanced disease or post-48 months from previous pregnancies, have a poor prognosis and require new treatment options.