Publications by authors named "K M Bogie"
The major populations at risk for developing pressure ulcers are older adults who have multiple risk factors that increase their vulnerability, people who are critically ill and those with spinal cord injury/disease. The reported prevalence of pressure ulcers in the United States is 2.5 million.
View Article and Find Full Text PDFBackground: Epigenetics studies the impact of environmental and behavioral factors on stable phenotypic changes; however, the state of the science examining epigenomic mechanisms of regulation related to secondary health conditions (SHCs) and neuroepigenetics in chronic spinal cord injury (SCI) remain markedly underdeveloped.
Objective: This scoping review seeks to understand the state of the science in epigenetics and secondary complications following SCI.
Methods: A literature search was conducted, yielding 277 articles.
Article Synopsis
- - The study aimed to identify genetic biomarkers linked to the risk of recurrent pressure injuries (PIs) in individuals with spinal cord injuries (SCI), focusing on veterans receiving care at specialized centers.
- - Researchers conducted thorough assessments over several years, analyzing blood samples and health records to explore genetic variations and their connection to PI history, specifically identifying 260 genes related to fat metabolism and biological processes.
- - Findings suggest that integrating genomic data with electronic health records could enhance the management of complex health issues like PIs in SCI patients, potentially enabling better-targeted care for higher-risk individuals.
Chronic ischemic wounds affect millions of people causing significant pain and disability. They can be considered to be stalled in the inflammatory stage and cannot heal without additional measures. A valid animal model is necessary to evaluate the efficacy of topical wound healing therapies and wearable technologies.
View Article and Find Full Text PDFObjective: The study describes the development and testing of a dry surface stimulation flexible electrode (herein referred to as Flexatrode), a low-cost, flexible, and scalable elastomeric nanocomposite using carbon black (CB) and polydimethylsiloxane (PDMS).
Methods: Flexatrodes composed of CB and PDMS were developed and tested for mechanical and functional stability up to 7 days. Uniform CB distribution was achieved by optimizing the dispersion process using toluene and methyl-terminated PDMS.