Publications by authors named "K M Archana"
Article Synopsis
- The study investigates the effectiveness of two pain management techniques, paravertebral block (PVB) and erector-spinae block (ESPB), for treating patients with acute herpes zoster (AHZ) to prevent postherpetic neuralgia (PHN).
- A total of 60 patients were randomly assigned to receive either standard treatment alone, standard treatment with PVB, or standard treatment with ESPB, with pain relief evaluated over a 60-day period.
- Results showed significantly lower rates of PHN in the PVB and ESPB groups (40% and 45%, respectively) compared to the control group (80%), indicating both blocks are effective in reducing pain and preventing PHN progression.
Background: Ultrasonographic imaging has been recently become simple portable and non-invasive adjuvant for bedside assessment of anterior neck soft tissue thickness which when measured at different levels showed to have significant role in predicting difficult laryngoscopy.
Aims And Objectives: Primary objective was Ultrasonographic measurement of anterior neck soft tissue thickness at 3 levels -Distance from skin to hyoid bone (DSHB) -Distance from skin to thyrohyoid membrane (DSTM) -Distance from skin to anterior commissure of vocal cord(DSAC) and to compare and correlate the findings with Cooks modification of Cormack-Lehane score in predicting difficult laryngoscopy. Secondary objective was to compare and correlate the ultrasonographic measurements with conventional airway assessment methods.
Advancing Green Chemistry in Antiviral Therapeutics: A Comprehensive Review.
Curr Drug Res Rev
June 2024
Cytomegalovirus (CMV) is a prevalent virus across the world that belongs to the family Herpesviridae but remains dormant in the body unless the immune system is compromised. In addition, when the bacterium is compromised without any health risks, the infection spreads from one person to another person through body fluids, such as saliva, blood, etc. Ganciclovir is an anti- viral medication used in treating viral infections, especially in the treatment of CMV in people with acquired immune deficiency syndrome and immunity at risk.
View Article and Find Full Text PDFAntibacterial Efficacy and Mechanisms of Action of a Novel Beta-Defensin from Snakehead Murrel, Channa striata.
Probiotics Antimicrob Proteins
July 2024
Article Synopsis
- Beta-defensins from fish are important antimicrobial peptides that help fight bacterial infections in aquatic species, and this study focuses on CsDef, a specific peptide from the snakehead murrel.
- CsDef was produced recombinantly, showing strong antibacterial activity against various fish pathogens, with notable efficacy measured by MIC and percentage inhibition rates.
- The peptide operates through multiple mechanisms against bacteria, is safe for human red blood cells and mammalian cells, demonstrates anticancer potential, and shows stability under diverse conditions, suggesting it could be useful in aquaculture applications.
Antimicrobial peptides (AMPs), including beta-defensin from fish, are a crucial class of peptide medicines. The focus of the current study is the molecular and functional attributes of CmDef, a 63-amino acid beta-defensin AMP from Malabar trevally, Carangoides malabaricus. This peptide demonstrated typical characteristics of AMPs, including hydrophobicity, amphipathic nature, and +2.
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