Publications by authors named "K M Al-Ghamdi"
Article Synopsis
- The pomegranate peel is rich in phenolic compounds, which have medicinal and commercial value, but their concentrations and biological activities during different ripening stages are not well understood.
- Extracts from pomegranate peels at various growth stages (40, 80, and 120 days) were tested, with stage 2 and stage 3 showing strong antimicrobial effects.
- Notably, the stage 2 extract was most effective against lung, breast, and liver cancer cells, and further analysis confirmed γ-Sitosterol as a key compound responsible for its antimicrobial and cytotoxic properties, although more testing is required to confirm these findings.
Article Synopsis
- * This study examined how oxytocin (OXT) affects melanocyte functions, finding that OXT boosts the proliferation and migration of human melanocytes in a dose-dependent manner.
- * OXT also enhances the expression of proteins linked to melanin production and increases overall melanin output, suggesting that the OXT system could be a promising target for treating skin pigmentary disorders.
Mercury, a highly toxic metal and pollutant, poses a significant risk to human health and the environment. This study describes the synthesis of a new nitrogen-doped heteroaromatic hyper-crosslinked polyamine () via the polycondensation of 2,6-diaminopyrazine and tris(4-formylphenyl)amine for the efficient removal of mercury ions from aqueous solutions. The polymer was characterized by solid-state C-NMR and FT-IR spectroscopy.
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- BTBGD is a rare genetic disorder caused by mutations in the SLC19A3 gene, leading to severe neurological symptoms like confusion, seizures, and disabilities.
- Diagnosis is challenging due to the disease's rarity and varied symptoms, with current treatment involving thiamine and biotin supplementation, although long-term effectiveness is still unclear.
- Researchers have created induced pluripotent stem cell (iPSC) lines from a BTBGD patient, which can help study the disease's mechanisms and potentially lead to new treatments.
Article Synopsis
- The study created a tool to evaluate surgical videos, addressing gaps in current evaluation methods that focus mainly on written content.
- The tool was tested with expert feedback, resulting in 23 criteria assessing educational value, accuracy, and clarity in surgical demonstrations.
- Analysis of 25 YouTube videos on elliptical excision revealed that while their quality was fair to good, there's a need for improved video production to enhance educational value.