Identification of Dengue Virus Serotype and Genotype: A Comprehensive study from AIIMS Patna, Bihar.

Purpose: Dengue virus, a major global health concern, exhibits significant genetic diversity, leading to distinct serotypes and genotypes. Dengue is the second most common disease spread by mosquitoes that infect humans, after malaria. In recent decades, there has also been a shift in the tendencies of virus transmission from urban to peri-urban and rural settings.

Investigation of biometabolites and novel antimicrobial peptides derived from promising source Cordyceps militaris and effect of non-small cell lung cancer genes computationally.

Mushrooms are considered one of the safe and effective medications because they have great economic importance due to countless biological properties. Cordyceps militaris contains bioactive compounds with antioxidant, antimicrobial and anti-cancerous properties. This study was projected to analyze the potentials of biometabolites and to extract antimicrobial peptides and protein from the C.

The Role of Sirtuins in Diabetic Nephropathy: A Comprehensive Review.

Introduction: Diabetic nephropathy is characterized by elevated oxidative stress and chronic inflammation in the kidneys. A class of proteins called sirtuins is well-known to be important for a number of cellular functions, such as metabolism, stress tolerance, and ageing. Among them, SIRT1 is associated with the progression of diabetic nephropathy, a dangerous kidney-related consequence of diabetes mellitus.

Therapeutic Potential of Plant Phenolic Acids Combating Cancer Drug Resistance.

Despite notable progress in treatment modalities, cancer continues to be a prom-inent cause of death globally. Chemotherapy is the main method used to treat cancer, and chemotherapeutic medications are categorized according to how they work. Nevertheless, the issue of multidrug resistance (MDR) is a significant obstacle, impacting almost 90% of cancer patients who receive chemotherapy or innovative targeted medicines.

Chemical characteristics and bioactivity potential of polysaccharide extracts and purified fractions from Arctic brown macroalgae.

Macroalgae growing in the polar regions are exposed to extreme environment conditions and may induce differences in the structural and bioactive properties of their polysaccharides. Six brown macroalgae viz. kelp species - Saccharina latissima, Laminaria digitata, and Alaria esculenta; rockweed Fucus distichus; and filamentous macroalgae - Chorda filum and Chordaria flageliformis, from the Arctic were investigated for polysaccharides and their bioactivity.