Publications by authors named "K Lotfi"
Article Synopsis
- A systematic review and meta-analysis was conducted to explore the connection between monounsaturated fatty acids (MUFAs) and stroke risk, revealing mixed results across different studies.
- The analysis included 11 cohort studies with data from over 475,000 participants, indicating that higher MUFA consumption is linked to a reduced risk of total stroke and specifically hemorrhagic stroke, but not ischemic stroke.
- The study suggests that increasing MUFA intake could have important public health implications by potentially lowering the risk of certain types of strokes.
Context: Existing evidence on the relation between folate intake and biomarkers with mortality risk is controversial.
Objective: Previous cohort studies were examined regarding folate intake and biomarkers in relation to risk of all-cause, cardiovascular disease- (CVD), and cancer-related mortality through a systematic review and meta-analysis.
Data Sources: A systematic search was performed of the PubMed, Scopus, and ISI Web of Science databases up to July 2023.
Diet quality has been associated with mental health, and recently, there has been growing interest in the association between the sustainability of diets and human health. The objective of this cross-sectional study was to explore the relationship between a newly developed dietary index for health and sustainability and psychological disorders among Iranian women. Participants in this cross-sectional study included 479 women living in Tehran with no history of chronic disease.
View Article and Find Full Text PDFBackground And Aims: There is a lack of evidence on dietary intake of methyl donor nutrients with metabolic health status and related biomarkers. Thus, this study aimed to assess the relation between methyl donor nutrients intake and metabolic health status with regarding the interactive roles of brain-derived neurotrophic factor (BDNF) and adropin in Iranian adults.
Methods: This cross-sectional survey was conducted among 527 Iranian adults (45.
BCR::ABL1-independent pathways contribute to primary resistance to tyrosine kinase inhibitor (TKI) treatment in chronic myeloid leukemia (CML) and play a role in leukemic stem cell persistence. Here, we perform ex vivo drug screening of CML CD34 leukemic stem/progenitor cells using 100 single drugs and TKI-drug combinations and identify sensitivities to Wee1, MDM2, and BCL2 inhibitors. These agents effectively inhibit primitive CD34CD38 CML cells and demonstrate potent synergies when combined with TKIs.
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