Publications by authors named "K Lillie-Jaschniski"
Background: Salmonella is widespread in pig husbandry and pork is an important source for human salmonellosis. Surveillance programmes are conducted in many European countries and various management measures are implemented on farm level to control Salmonella. Piglet or maternal vaccination can reduce Salmonella shedding and lower the likelihood of piglet infection.
View Article and Find Full Text PDFBackground: Aggregated samples such as oral fluids (OFs) display an animal friendly and time and cost-efficient sample type for swine Influenza A virus (swIAV) monitoring. However, further molecular and biological characterization of swIAV is of particular significance. The reportedly inferior suitability of aggregated samples for subtyping of swIAV presents a major drawback compared to nasal swabs, still considered the most appropriate sample type for this purpose (Garrido-Mantilla et al.
View Article and Find Full Text PDFArticle Synopsis
- Swine influenza A viruses (swIAV) are a significant respiratory disease in pigs, causing economic challenges in pig farming due to ongoing virus transmission and variation.
- Researchers immunized antibody-positive piglets from an infected herd using a prime-boost vaccination strategy with novel vaccines (a live attenuated influenza virus and a vesicular stomatitis virus-based replicon).
- These new vaccines significantly reduced virus replication in vaccinated piglets compared to traditional inactivated virus vaccines, potentially helping to control virus spread and improving animal health while lowering the risk of transmission to humans.
Background: Monitoring of infectious diseases on swine farms requires a high diagnostic sensitivity and specificity of the test system. Moreover, particularly in cases of swine influenza A virus (swIAV) it is desirable to include characterization of the virus as precisely as possible. This is indispensable for strategies concerning prophylaxis of swIAV and furthermore, to meet the requirements of a purposeful monitoring of newly emerging swIAV strains in terms of vaccine design and public health.
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- Respiratory disease significantly impacts pig farming economics, with swine influenza A viruses (swIAV) being a common cause among European pig populations, linked to their zoonotic potential seen in past human pandemics.
- Monitoring and control of these pathogens rely on advanced diagnostic techniques, including multiplex quantitative reverse transcription real-time PCRs (mRT-qPCR) and new sequencing methods to accurately detect swIAV.
- Despite a large number of samples showing negative results for swIAV, co-infections with other viruses, specifically porcine respirovirus 1 (PRV1) and swine orthopneumovirus (SOV), indicate these may play significant roles in enhancing respiratory diseases in pigs.