Publications by authors named "K Leffondre"
Article Synopsis
- The study investigated the link between air pollution and cataract surgery incidence in older adults in Bordeaux, France.
- Researchers followed 829 participants aged 65 and older from 1999-2017, monitoring their cataract surgeries and estimating their long-term air pollution exposure.
- Results showed that long-term exposure to nitrogen dioxide (NO) at levels ≥40 μg/m was significantly associated with increased incidence of cataract surgery, suggesting that meeting air quality standards could benefit public health.
Background: While genetic, hormonal, and lifestyle factors partially elucidate the incidence of breast cancer, emerging research has underscored the potential contribution of air pollution. Polychlorinated biphenyls (PCBs) and benzo[a]pyrene (BaP) are of particular concern due to endocrine-disrupting properties and their carcinogenetic effect.
Objective: To identify distinct long term trajectories of exposure to PCB153 and BaP, and estimate their associations with breast cancer risk.
Article Synopsis
- A study investigated how exposure to various air pollutants affects mortality in dialysis patients, using data from 90,373 patients in France between 2012 and 2020.
- The research found that higher pollution levels were linked to increased all-cause deaths and specifically higher rates of infectious mortality among these patients.
- Results indicate that air pollution could be a significant factor in the rising deaths related to chronic kidney disease (CKD) globally, with stronger effects observed in women and patients with fewer comorbidities.
Article Synopsis
- The study investigates the link between social deprivation and the incidence of kidney replacement therapy (KRT) among children and young adults in France, showing a correlation between higher social deprivation and increased KRT rates.
- Analyzed data from 2010 to 2015, including 672 children who started KRT, revealing that 38.8% were from the most deprived areas, with higher incidence rates as deprivation increased.
- Results indicate that social health inequalities emerge even at the initiation of KRT, emphasizing the importance of addressing these inequalities in chronic kidney disease management.