Publications by authors named "K Le Prigent"

World Health Organization (WHO) grade III anaplastic meningioma is scarce. In this way, most studies compared WHO grade I and II. Otherwise, some authors are uncertain about using 18 F-FDG as a diagnostic tool to estimate the WHO grade, especially high.

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Article Synopsis
  • Thoracic radiation therapy can lead to accelerated atherosclerosis and aortic valve stenosis (AS), prompting this study to investigate targeted aortic valve irradiation effects in mice.
  • The study used echocardiography and MRI to assess AS and aortic inflammation, finding a significant increase in peak aortic jet velocity and remodeling in ApoE mice after irradiation.
  • The results indicate that targeted radiation can model aortic valve remodeling similar to human conditions, particularly in ApoE mice, suggesting the potential for future therapeutic interventions.
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F-FDG PET/CT plays an increasingly pivotal role in the staging and post-treatment monitoring of high-risk melanoma patients, augmented by the introduction of therapies, including tyrosine kinase inhibitors (TKI) and immune checkpoint inhibitors (ICIs), that have novel modes of action that challenge conventional response assessment. Simultaneously, technological advances have been regularly released, including advanced reconstruction algorithms, digital PET and motion correction, which have allowed the PET community to detect ever-smaller cancer lesions, improving diagnostic performance in the context of indications previously viewed as limitations, such as detection of in-transit disease and confirmation of the nature of small pulmonary metastases apparent on CT.This review will provide advice regarding melanoma-related PET protocols and will focus on variants encountered during the imaging of melanoma patients.

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Biomedical imaging technologies offer identification of several anatomic and molecular features of disease pathogenesis. Molecular imaging techniques to assess cellular processes in vivo have been useful in advancing our understanding of several vascular inflammatory diseases. For the non-invasive molecular imaging of vascular inflammation, nuclear medicine constitutes one of the best imaging modalities, thanks to its high sensitivity for the detection of probes in tissues.

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