Publications by authors named "K Land"
Background: Several adult studies show mixed reports in clinical outcomes between cryopreserved and fresh stem cell products, with majority reporting no significant differences and others report that there are differences in outcomes. There is limited literature reporting its impact on outcomes in pediatric hematopoietic cell transplantation (HSCT).
Objective: To compare clinical outcomes between fresh vs cryopreserved stem cell treatment in pediatric HSCT.
Article Synopsis
- - Patient loss to follow-up due to expensive and centralized diagnostics for tuberculosis is a major challenge, stressing the need for a more accessible testing method.
- - Current biomarkers, specifically antibodies against mycolic acids in mycobacterial cell walls, show potential but are hard to detect with typical rapid tests because they are of low affinity.
- - Researchers have developed a new method for detecting mycolic acid antibodies using engineered monoclonal antibodies, leading to the creation of a novel lateral flow immunoassay called MALIA, which shows promise for practical tuberculosis testing.
Article Synopsis
- * Most existing studies focus on single phthalate exposures in animal models, leaving the effects of real-life mixtures and their impacts on women's reproductive health largely unexamined.
- * Recent literature indicates that high phthalate exposure is linked to menstrual irregularities, ovarian disorders, poor IVF outcomes, and adverse pregnancy results, highlighting the need for better research on phthalate mixtures and their mechanisms of toxicity.
Article Synopsis
- This study investigates why females generally have longer lifespans than males, revealing that genetic factors linked to longevity are more significant in females based on extensive analysis of data from centenarians in China.
- The research highlights that findings are consistent across various regions in China and are supported by analyses involving a large dataset of over 5,000 centenarians, indicating a potentially global pattern in genetic associations with longevity.
- The study suggests moving away from a "one-size-fits-all" approach in healthcare, encouraging tailored medical interventions that account for sex-based genetic differences and their impacts on health outcomes.
Article Synopsis
- * Some blood centers defer donors based on medication use to protect product quality and minimize risks of transmissible diseases.
- * The impact of a one-time exposure to medication in donated blood is significantly different from continuous medication use, making the likelihood of negative effects on recipient safety quite low.