[Assessment of medication prescribing in a geriatric follow-up care and rehabilitation].

The aim of the study was to analyse the prescriptions and identify the factors associated with inappropriate prescribing (IP) and polypharmacy. Polypharmacy and IP concerned 80% of the 54 patients included in the study upon admission, and 78% upon discharge without a statistically significant reduction. A critical analysis of prescriptions would help to reduce inappropriate prescribing and polypharmacy in elderly patients.

[Physicians and advance directives in geriatric setting].

Advance directives (AD) are not sufficiently applied in geriatric setting despite their widespread dissemination since the publication of Claeys-Leonetti law. The aim of this study was to analyze geriatricians' knowledge of the concept of AD and to evaluate their practices in the process of patient information and AD collection.

Should patients with asymptomatic pompe disease be treated? A nationwide study in France.

Introduction: Acid α-glucosidase deficiency, that is, Pompe disease, is a glycogenosis for which enzyme replacement therapy (ERT) is available. It is not known whether patients diagnosed at an asymptomatic stage should be treated to prevent progression of the disease.

Methods: We investigated 7 patients with asymptomatic Pompe disease identified from the French Pompe registry.

The French Pompe registry. Baseline characteristics of a cohort of 126 patients with adult Pompe disease.

Pompe disease is a rare autosomal recessive muscle lysosomal glycogenosis, characterised by limb-girdle muscle weakness and frequent respiratory involvement. The French Pompe registry was created in 2004 with the initial aim of studying the natural history of French patients with adult Pompe disease. Since the marketing in 2006 of enzyme replacement therapy (alglucosidase alfa, Myozyme(®)), the French Pompe registry has also been used to prospectively gather the biological and clinical follow-up data of all adult patients currently treated in France.