Publications by authors named "K L Wallace"
Introduction: Genetic studies of smoking cessation have been limited by short-term follow-up or cross-sectional design. Within seven genes (CHRNA3, CHRNA5, CHRNB2, CHRNB4, DRD2, DBH and CYP2A6) influencing biological mechanisms relevant to smoking, this study aimed to identify single nucleotide polymorphisms (SNPs) associated with smoking cessation throughout up to 38-years of follow-up.
Methods: Participants were from two all-female cohort studies, Nurses' Health Study (NHS) (n = 10,017) and NHS-2 (n = 2,793).
Introduction: Women with hypertensive disorders of pregnancy such as HELLP (hemolysis, elevated liver enzyme, low platelet) Syndrome are affected by acute kidney injury during pregnancy (PR-AKI) at higher rates than women without hypertension. Both hypertensive disorders of pregnancy and Acute Kidney Injury (AKI) outside the context of pregnancy have been associated with an increased risk of developing Chronic Kidney Disease (CKD) and cognitive impairment. In our current study, we set out to determine if PR-AKI led to the development of CKD and impaired cognition in the postpartum period and if HELLP syndrome exacerbates the impairments.
View Article and Find Full Text PDFBackground: More than 16% of children in the U.S. have a behavioral health (BH) disorder but less than half receive recommended care.
View Article and Find Full Text PDFArticle Synopsis
- Preeclampsia (PE) is linked to hypertension and immune responses during pregnancy, with COVID-19 history potentially increasing PE-like symptoms and cognitive issues in affected individuals.
- * Researchers isolated CD4+ T cells from women with PE and those without (some with COVID-19 history) and injected them into pregnant rats to study their impact on blood pressure and cognitive function.
- * The study found that PE, particularly with a COVID-19 history, caused higher blood pressure and cognitive dysfunction in recipient rats, suggesting a significant role of CD4+ T cells in these pregnancy complications.
Pregnancy Outcomes of Women Veterans with Autoimmune Disease.
Womens Health Rep (New Rochelle)
September 2024
Article Synopsis
- Women Veterans (WV) have unique risk factors for autoimmune diseases (AID) that can lead to pregnancy complications.
- A study identified 25 WV with AID, finding that conditions like inflammatory bowel disease, psoriasis, and undifferentiated connective tissue disease were the most common.
- The research revealed 44% of these women faced pregnancy complications, with a significant number not using VA health services for care during their pregnancies.