Redefining piscine lactococcosis.

Unlabelled: Piscine lactococcosis is a significant threat to cultured and wild fish populations worldwide. The disease typically presents as a per-acute to acute hemorrhagic septicemia causing high morbidity and mortality, recalcitrant to antimicrobial treatment or management interventions. Historically, the disease was attributed to the gram-positive pathogen .

Serovar Dublin from Cattle in California from 1993 to 2019: Characterization and Analysis of Antimicrobial Resistance Diversity.

For this study, antimicrobial susceptibility data for enterica subsp. enterica serovar Dublin (S. Dublin)-a well-known cattle-adapted pathogen with current concerns for multidrug resistance-were recovered from cattle at the California Animal Health and Food Safety Laboratory System (CAHFS) over the last three decades (1993-2019) and were evaluated using tools to capture diversity in antimicrobial resistance.

-positive , a novel teleost pathogen isolated from cultured barramundi.

Members of the genus are emergent pathogens of cultured eels, as well as several characid and cyprinid species. Since 2013, has been reported from diseased barramundi () cultured in North America; we recovered 8 isolates from diseased fish during different outbreaks from the same farm. The isolates from barramundi were compared phenotypically and genetically to isolates characterized from ornamental fish and recovered from aquatic and terrestrial animals.

Serovar from Cattle in California from 1993-2019: Antimicrobial Resistance Trends of Clinical Relevance.

subsp. serovar () is a cattle-adapted pathogen that has emerged as one of the most commonly isolated and multidrug resistant (MDR) serovars in cattle. may be shed in feces, milk, and colostrum and persist in asymptomatic cattle, leading to spread and outbreaks in herds.

A review of guidelines for evaluating a minor modification to a validated assay.

Any modification to a validated assay must be evaluated in terms of the impact on the assay's performance characteristics and whether the assay remains fit for the intended purpose. The comparison is referred to as a 'method comparison', 'method comparability', 'method change', or 'comparative validation'. This review presents recommendations and examples of studies found in the current literature as a means of assessing minor modifications.