Publications by authors named "K L Richardson"
Article Synopsis
- The study investigates CP symmetry violation in the decay of D^{+} particles into K^{-}K^{+}π^{+} using data from proton-proton collisions at a high energy of 13 TeV.
- A unique model-independent method was employed to analyze the phase-space distributions of D^{+} and D^{-} particles, correcting for any instrumental biases using D_{s}^{+} decays.
- The findings indicate no significant evidence of CP violation, with a p value of 8.1%, and measure specific CP asymmetry observables, marking this study as the most sensitive search of its kind in multibody decays.
Syphilitic hepatitis is a rare manifestation of a sexually transmitted infection. Given its nonspecific presentation, it is important for clinicians to consider the diagnosis in sexually active patients presenting with elevated liver tests. In this case, a 30-year-old man presented with an itchy rash and was diagnosed with an allergic reaction.
View Article and Find Full Text PDFBackground: Continuous glucose monitoring (CGM) holds potential as a precision public health intervention, offering personalised insights into how diet and physical activity affect glucose levels. Nevertheless, the efficacy of using CGM in populations with and without diabetes to support behaviour change and behaviour-driven outcomes remains unclear. This systematic review and meta-analysis examines whether using CGM-based feedback to support behaviour change affects glycaemic, anthropometric, and behavioural outcomes in adults with and without diabetes.
View Article and Find Full Text PDFArticle Synopsis
- Dentatorubral-pallidoluysian atrophy (DRPLA) is a neurodegenerative disease characterized by symptoms like ataxia, dementia, and epilepsy, caused by an expansion of CAG repeats in the ATROPHIN 1 (ATN1) gene.
- Researchers developed Drosophila (fruit fly) models that express either normal ATN1 (Q7) or a pathogenic version with expanded repeats (Q88), revealing that the pathogenic variant significantly reduces fly motility, lifespan, and affects internal structures more severely than the normal version.
- RNA sequencing identified pathways related to protein quality control that are altered by pathogenic ATN1, and subsequent genetic experiments highlighted the
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Human Papillomavirus-Related Oropharyngeal Cancer.
JAMA Otolaryngol Head Neck Surg
December 2024
Article Synopsis
- - The study examines the effectiveness of a treatment strategy combining neoadjuvant chemotherapy (NECTORS) followed by surgery in preventing distant metastasis (DM) in patients with HPV-related oropharyngeal cancer, compared to standard care with concurrent chemoradiation (CCRT).
- - It includes 342 patients with advanced HPV-positive OPSCC, showing that NECTORS resulted in no cases of distant-only metastasis and fewer overall recurrences than CCRT.
- - The analysis considers various factors like age, sex, and cancer stage to assess DM-free survival rates, highlighting the potential benefits of NECTORS in reducing treatment-related toxicity.