Publications by authors named "K L Pierce"

Article Synopsis
  • The study analyzed preoperative data from adult spinal deformity patients to establish a threshold for T1 slope (T1S) from cervical radiographs that indicates thoracolumbar malalignment.
  • Researchers found a specific cutoff of 30 degrees for high T1S, with 50% of the patients falling above this threshold.
  • Notably, higher T1S was linked with greater thoracic kyphosis, sagittal vertical axis, T1-pelvic angle, and pelvic tilt, suggesting that this measurement could serve as a useful parameter in cervical evaluations.
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Background: Exposure to polycyclic aromatic hydrocarbons (PAHs) during childhood has been associated with altered growth and adiposity in children. The effects of prenatal exposure to PAHs on developmental programming of growth and adiposity are still unknown.

Objective: To study the association of prenatal exposure to PAHs with early childhood growth and adiposity measures.

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Vaccination with the tetravalent live attenuated dengue virus (DENV) vaccines TV003 and TV005 causes a mild, relatively localized erythematous maculopapular skin rash in most dengue-naïve vaccinees. Human challenge model DENV strains, DENV2Δ30 and DENV3Δ30, trigger a confluent skin rash over most of the body in most unvaccinated participants. To determine the etiology of these rashes we performed in situ hybridization for DENV genome and assessed cellular infiltration by hematoxylin/eosin staining in skin biopsies from humans infected with live attenuated dengue vaccine DENV2Δ30 or DENV3Δ30 challenge strains.

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Article Synopsis
  • ALSUntangled examines alternative treatments for ALS, focusing on psilocybin, a psychedelic compound from mushrooms.
  • Psilocybin may theoretically help slow ALS due to its ability to cross the blood-brain barrier and influence neurogenesis and inflammation, but there's no existing research specifically on its effects in ALS patients.
  • Due to potential risks of psychological side effects and lack of supporting evidence, the use of psilocybin for ALS progression is not currently endorsed.
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