Publications by authors named "K L Parmar"

Introduction: Prehabilitation aims to improve physiological reserve and psychological resilience, enabling patients to better tolerate the physiological stress of major surgery, thereby reducing the risk of complications and improving surgical outcomes. In this review, we provide an update of the development of prehabilitation in patients having cancer surgery.

Methods: We searched databases of peer-reviewed research to identify appropriate papers.

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The TRPC3 protein plays a pivotal role in calcium signaling, influencing cell function. Aberrant TRPC3 expression is implicated in various pathologies, including cardiovascular diseases, tumors, and neurodegeneration. Despite its functional similarities with TRPC6 and TRPC7, TRPC3 exhibits distinct roles in disease contexts.

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Article Synopsis
  • PARG (poly (ADP-ribose) glycohydrolase) is an enzyme that helps repair DNA by removing poly (ADP-ribose), and inhibiting it can lead to increased DNA damage and sensitize cancer cells to treatments.
  • Inhibiting PARG leads to the buildup of single-stranded DNA gaps (ssGAPs) during DNA replication, similar to the effects of PARP inhibitors, particularly in cancer cells that are sensitive to treatment.
  • Research shows that treatment with PARG inhibitors (PARGi) not only affects homologous recombination-deficient cancer cells but also has potential effectiveness in certain homologous recombination-proficient tumors, suggesting patient-derived organoids could be key
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The emergence of multidrug-resistant Klebsiella pneumoniae poses significant clinical challenges with limited treatment options. Biofilm is an important virulence factor of K. pneumoniae, serving as a protective barrier against antibiotics and the immune system.

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We report a significant enhancement in the thermoelectric power of PEDOT by fabricating a novel ternary composite film by incorporating BiTe and rGO. A series of five samples of PEDOT:PSS/BiTe/rGO ternary composite films were synthesized using a spin coating method and having different weight% (0.0, 0.

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