Increased risk of serious injury following an initial prescription for diphenhydramine.

Background: Diphenhydramine may be associated with excess risk of injury relative to nonsedating H1-receptor antagonists.

Objective: This study sought to compare the risk of injury in patients exposed to diphenhydramine with the risk of injury in patients exposed to loratadine.

Methods: A retrospective cohort study of injury was carried out in 12,106 patients whose initial antihistamine prescription was for diphenhydramine and in 24,968 patients whose initial antihistamine prescription was for loratadine.

Structured data management--the design and implementation of a web-based video archive prototype.

In response to the lack of readily available multimedia rich medical knowledge sources to support medical education and patient care, we designed and implemented a web-based video publishing platform. In order to promote the development of high-quality, up-to-date educational content, we have devised a scalable structure that allows online submissions and continuous updating of video and accompanying textual descriptions. Our goal is to enable experts in varied medical domains to collaborate in the construction of a video library using an intuitive web-based interface.

Versatile user interface using UMLS Metathesaurus.

One of the obstacles for a successful search in the biomedical field is that different vocabularies are used by different databases but more than one database is usually needed to respond adequately to a healthcare professional's query. A typical searcher usually is unfamiliar with these vocabularies and the sophisticated measures to narrow or broaden a search. As a result, a failed search is often due to using "inappropriate" search terms.

What's related? Generalizing approaches to related articles in medicine.

Introduction: We did formative evaluations of several variations to the computation of related articles for non-bibliographic resources in the medical domain.

Methods: A binary model and several variations of the vector space model were used to measure similarity between documents. Two corpora were studied, using a human expert as the gold standard.