Combination Antithrombotic Therapy for Reduction of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease.

Background: Stroke secondary to intracranial atherosclerotic disease (ICAD) is associated with high recurrence risk despite currently available secondary prevention strategies. In patients with systemic atherosclerosis, a significant reduction of stroke risk with no increase in intracranial or fatal hemorrhage was seen when rivaroxaban 2.5 mg twice daily was added to aspirin.

Low field electrocaloric effect at isotropic-ferroelectric nematic phase transition.

Electrocaloric effects (ECE) in solid state materials, such as ferroelectric ceramics and ferroelectric polymers, have a great impact in developing cooling systems. Herein, we describe the ECE of a newly synthesized ferroelectric nematic liquid crystal compound at the isotropic-ferroelectric nematic (I-N) phase transition. While the Joule heat completely suppressed the ECE in a DC field, in an AC field with < 1.

Automatic Matching Algorithms to Identify Eligible Participants for Stroke Trials: A Proof-of-Concept Study.

Background: Clinical trials often struggle to recruit enough participants, with only 10% of eligible patients enrolling. This is concerning for conditions like stroke, where timely decision-making is crucial. Frontline clinicians typically screen patients manually, but this approach can be overwhelming and lead to many eligible patients being overlooked.