Publications by authors named "K L Gonzales"

Objectives: This study aimed to compare the levels of depression, anxiety, and stress, and the coping styles among physicians and nurses in a COVID-19 referral hospital in Manila from June to July 2020.

Methods: A cross-sectional study among medical residents and nurses selected via convenience sampling was employed. Data were obtained through COVID Stressors and Stress Reduction Questionnaire, Depression, Anxiety, and Stress Scale-21, and Filipino Coping Strategies Scale.

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Article Synopsis
  • The study focuses on identifying predictive biomarkers for hepatocellular carcinoma (HCC) related to metabolic dysfunction-associated steatotic liver disease (MASLD) by examining the gut microbiome and liver gene expression in mice with altered Pten genes.
  • Findings reveal that changes in gut microbiome composition correlate with tumor presence, particularly in mice with multiple tumors, while specific gene expression changes in the liver are linked to tumor burden and inflammation.
  • The research uncovers potential microbiome factors and gene expression patterns that drive liver cancer development, which could aid in creating new prevention strategies and risk assessment tools for HCC.
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Detecting and screening clouds is the first step in most optical remote sensing analyses. Cloud formation is diverse, presenting many shapes, thicknesses, and altitudes. This variety poses a significant challenge to the development of effective cloud detection algorithms, as most datasets lack an unbiased representation.

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Objective: To understand the perspectives of key informant experts regarding the relationship between food insecurity and gestational diabetes mellitus risk reduction behaviors among young American Indian and Alaska Native females.

Methods: Participants were adult key informants with expertise in food/nutrition and health within Tribal communities (N = 58) across the US. Data were collected through 1:1 interviews using a semistructured moderator guide and analyzed using thematic content analysis methods.

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The gut microbiota drives progression to liver fibrosis, the main determinant of mortality in metabolic dysfunction-associated steatohepatitis (MASH). In this study, we aimed to identify bacterial species associated with protection against liver fibrosis in a high-risk population, and test their potential to protect against liver fibrosis . Based on stool shotgun metagenomic sequencing of 340 subjects from a population cohort disproportionally affected by MASH, we identified bacterial species from the and orders associated with reduced risk of liver fibrosis.

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