Publications by authors named "K L Chaffin"

Background/objectives: Individuals are turning increasingly towards online resources, such as TikTok, to educate themselves on their medical conditions. Polycystic ovary syndrome (PCOS) is a prominent example, as women report dissatisfaction with the diagnosis process and treatment options. This study aims to provide a content analysis of the quality of PCOS health information on TikTok.

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  • The study focuses on the growing trend of patients using online platforms to seek medical information about primary headaches, highlighting the potential for encountering misinformation.
  • It aims to evaluate the quality and extent of online content related to conditions like migraines and cluster headaches, while identifying gaps in knowledge that can assist healthcare providers.
  • The methodology includes a systematic review of various community forums and social media platforms, with a descriptive data analysis and results expected to be shared in a peer-reviewed journal.
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  • - The study investigates the chemical stability of different transvenous lead materials, focusing on Optim leads, by analyzing the molar mass of extracted pacing and defibrillator leads from Emory University Hospitals.
  • - Researchers examined 70 extracted leads, comparing the chemical degradation of insulation materials like poly(ether)urethane and Optim over various implant durations, with findings showing Optim's molar mass decreased to 40% after 10 years.
  • - The reduction in molar mass for Optim indicates potential premature insulation defects, which correlates with higher rates of electrical malfunctions observed in these cardiac leads.
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Intervertebral disc (IVD) degeneration is a common pathological condition associated with low back pain. Recent evidence suggests that mesenchymal signaling cells (MSCs) promote IVD regeneration, but underlying mechanisms remain poorly defined. One postulated mechanism is via modulation of macrophage phenotypes.

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Introduction And Objectives: In clinical trials, patients with hepatitis C virus (HCV) genotype (GT)1a infection and baseline resistance-associated substitutions (RASs) at amino acid positions 28, 30, 31, or 93 receiving elbasvir/grazoprevir for 12 weeks achieved lower rates of sustained virologic response (SVR) than those without baseline RASs. SVR rates in patients with RASs were improved when elbasvir/grazoprevir treatment duration was extended from 12 to 16 weeks and administered concomitantly with ribavirin.

Materials And Methods: This was a retrospective, observational analysis using electronic health record abstraction.

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