Publications by authors named "K Kyono"

Background: Basal cell carcinoma is the most common skin malignancy. The standard treatment is surgical excision with predetermined margins. Some argue that the currently recommended surgical margins are excessive, and it is questionable whether such wide surgical margins should be applied to all lesions.

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Purpose: Are human embryos arising from two plus one small pronucleated zygotes, called 2.1 pronuclei (PN), clinically useful?

Methods: In a retrospective embryo cohort study and prospective experimental study, a total of 287 cycles in which at least one 2.1PN was identified in the fertilization check were included.

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Article Synopsis
  • This study introduces a new sperm retrieval technique called micromapping testicular sperm extraction (MMTSE) for treating nonobstructive azoospermia (NOA), aimed at providing a less invasive and more effective approach than traditional microscopic testicular sperm extraction (mTESE).
  • MMTSE involves dividing the testis into four sections and making small needle holes to extract tubules, while allowing for real-time assessment of tissue for sperm presence.
  • Results showed that all 15 patients in the sperm-positive group retrieved sperm successfully, while only 4 out of 25 in the sperm-negative group were successful with mTESE, highlighting MMTSE's potential benefits.
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Purpose: To evaluate clinical outcomes after endometrial receptivity analysis (ERA).

Methods: This was a multicenter, retrospective cohort study involving 861 women who underwent ERA testing at certified fertility clinics in Japan, and who received subsequent personalized blastocyst embryo transfers (ET) between 2018 and 2020. Clinical outcomes, including pregnancies, miscarriages, and live births, were evaluated according to receptivity status for ERA.

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Purpose: Increasing numbers of women are opting to undergo non-medical oocyte cryopreservation (NMOC). In this report, we present experience at our clinic and discuss NMOC in Japan.

Methods: We followed the progress of 403 women who underwent NMOC at our clinic between 2014 and 2021, totaling 592 reproductive cycles.

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