Publications by authors named "K Kuzume"

Atopic dermatitis (AD) may develop by 6 months of age, and its severity assessment is essential for appropriate treatments. Scoring Atopic Dermatitis (SCORAD) is suggested to evaluate the severity of AD but is cumbersome for routine clinical use. The serum thymus and activation-regulated chemokine (TARC) is used as a marker of AD severity.

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  • * A study explored the effects of bezafibrate on five VLCADD patients over four years, focusing on the frequency of myopathic attacks and hospitalizations.
  • * Results indicated that bezafibrate significantly reduced the number of severe attacks and improved patients' daily functioning, suggesting it may be an effective long-term treatment.
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Background: There are expanding indications for oral food challenges (OFCs). Although several studies have examined the risk of OFCs, little has been reported on allergic reactions during OFCs depending on the indication. This study assessed the prevalence, severity, and treatment of allergic reactions depending on the indication for OFCs.

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  • Fatty acid oxidation disorders (FAODs) are rare genetic diseases linked to dysfunctional mitochondrial enzymes, and a previous study indicated that bezafibrate, a type of medication, improved the quality of life (QOL) for these patients.
  • A recent follow-up study involved six patients, assessing their QOL over an extended period of 102 to 174 weeks after initial treatment, using the SF-36 questionnaire to measure various health components.
  • Results showed significant improvements in physical functioning and overall QOL, particularly among older patients, reinforcing the potential benefits of bezafibrate for individuals with FAODs.
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Background Trigeminal neuralgia is a neuropathic disorder characterized by episodes of intense pain in the face. Drug therapy is the first choice of treatment. However, in cases where drug therapy are contraindicated due to side effects, patients can get pain relief from lengthy neurosurgical procedures.

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