Publications by authors named "K Kusakabe"
The three-drug anesthetic mixture (medetomidine, midazolam and butorphanol), developed as an injectable anesthetic for laboratory animals, has been verified from various perspectives and applied to mice and other laboratory animals. However, the effects of its storage conditions and periods on its efficacy have not yet been studied. This study investigated the mixture's efficacy after storage under various conditions (room temperature, 4°C and -20°C) for 1 and 2 years.
View Article and Find Full Text PDFColor tests are advantageous for the field detection of illicit drugs because of their simplicity, low cost, and rapidity. The Scott test has been widely used as a color test for cocaine; however, it has the disadvantage of reacting with cathinone derivatives. To develop a more discriminating field-testing procedure, we evaluated the Cupric Reducing Antioxidant Capacity (CUPRAC) and bicinchoninic acid (BCA) tests for cathinones, to discriminate between cocaine and cathinones.
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- Popliteal artery injury, although rare, can lead to severe complications like limb ischemia and potential amputation, prompting the need for effective treatment strategies.
- The study analyzed patient records from two hospitals between 2011 and 2022, comparing treatment outcomes, particularly focusing on the time to reperfusion and types of interventions used for popliteal artery injuries.
- Results indicated that the hospital using temporary vascular shunting had significantly shorter reperfusion times and better clinical outcomes, suggesting the importance of prompt diagnosis and systematic treatment protocols.
Article Synopsis
- - The study focuses on improving the diagnosis of primary central nervous system lymphoma (PCNSL) during surgery by using intraoperative rapid immunohistochemistry (IHC), along with cytology and flow cytometry (FCM) for quicker and more accurate treatment decisions.
- - In a trial involving 35 patients from April 2020 to January 2024, the addition of cytology and FCM to rapid IHC significantly sped up the time from surgery to chemotherapy initiation for PCNSL (1.6 days versus 7.3 days), demonstrating the benefits of this combined approach.
- - Final pathological diagnoses confirmed the consistency of intraoperative rapid IHC results, and the combined method resulted in changes in treatment strategy in certain
During the screening of novel chemotherapeutic candidates from plants against adult T-cell leukaemia/lymphoma (ATL), we found that extracts of plants in the Solanaceae, Annonaceae, Apocynaceae, and Rutaceae families showed anti-proliferative activity in the MT-1 and MT-2 cell lines. We have isolated active compounds from these plants in the present research because Cupressaceae plants showed potent anti-proliferative activity in the cell lines. We attempted to isolate the active compounds from the leaves of .
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