Ten year survivorship after cemented and uncemented medial Uniglide® unicompartmental knee arthroplasties.

Background: Results of knee replacement registries have shown that unicompartmental knee arthroplasty (UKA) has a significantly higher revision and failure rate than current state-of-the-art TKA. The aim of this prospective study is to evaluate the long-term outcomes and to calculate the 10 year survival of knees with medial osteoarthritis treated with Uniglide® UKA.

Methods: Two hundred thirty-four patients were assessed by an independent clinical observer using the American Knee Society Clinical Rating System, a validated outcome measure.

[In vivo reactivation of reduced T cell activity following polytransfusion caused by immune aggregates in immunoglobulin preparations].

Surgery leads to an activation of peripheral blood lymphocytes, which is inhibited by polytransfusion. This effect could be eliminated by application of immunoglobulins. We think that immune aggregates in immunoglobulin preparations can stimulate T-lymphocytes.