Publications by authors named "K Krzyzowska"
Background: Nowadays, a reduced initial daily dose of tacrolimus (Tac) (0.1-0.15 mg/kg) is recommended for the majority of kidney transplant recipients (KTRs).
View Article and Find Full Text PDFBackground: Observational data suggest that the fixed initial recommended tacrolimus (Tc) dosing (0.2 mg/kg/day) results in supratherapeutic drug levels in some patients during the early posttransplant period. The aim of the study was to analyze a wide panel of patient-related factors and their interactions which increase the risk for first Tc blood level > 15 ng/ml.
View Article and Find Full Text PDFArticle Synopsis
- Kidney transplantation significantly lowers mortality for patients with ESKD from type 1 diabetes, but there's debate over whether to perform it alone or alongside pancreas transplantation.
- A study analyzed outcomes from 87 deceased donor kidney transplants and 66 simultaneous pancreas-kidney transplants, revealing that SPKTx patients had fewer cardiovascular events and higher kidney function but similar overall survival rates and graft survival compared to KTx recipients.
- While pancreas transplantation showed benefits in reducing cardiovascular risk and proteinuria, it did not enhance overall patient or kidney graft survival in the long-term follow-up.