Knockout Genes in Bowel Anastomoses: A Systematic Review of Literature Outcomes.

Background: The intestinal wound healing process is a complex event of three overlapping phases: exudative, proliferative, and remodeling. Although some mechanisms have been extensively described, the intestinal healing process is still not fully understood. There are some similarities but also some differences compared to other tissues.

Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla.

Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness. Banking of these stem cells can offer a source of dental stem cells for future regenerative therapies.

A tissue-engineered biocomplex for periodontal reconstruction. A proof-of-principle randomized clinical study.

Aim: To assess the safety/efficacy of a tissue-engineered biocomplex in periodontal reconstruction.

Methods: Twenty-seven intrabony defects were block-randomized across three treatment groups: Group-A (N  = 9) received autologous clinical-grade alveolar bone marrow mesenchymal stem cells (a-BMMSCs), seeded into collagen scaffolds, enriched with autologous fibrin/platelet lysate (aFPL). In Group-B (N  = 10), the collagen scaffold/aFPL devoid of a-BMMSCs filled the osseous defect.

Lens Epithelial Surface Disorders in Exfoliation Syndrome: A Scanning and Transmission Electron Microscopy Study.

Background: Hydrodissection was recently reported to occur more easily in patients with exfoliation syndrome (XFS). Transmission electron microscopy (TEM) studies have already revealed alterations of the lens epithelial cells (LECs) and their apical membrane towards the lens fibers.

Objective: The aim of this work was to examine the three-dimensional appearance of the lens epithelium in patients with XFS.

Synergistic Effect of Ischemic Preconditioning and Antithrombin in Ischemia-Reperfusion Injury.

Objectives: Our study aimed to determine whether antithrombin plays a synergistic role in accentuating the effects of intestinal ischemic preconditioning.

Materials And Methods: Fifty rats were randomly allocated to 5 groups (10 rats/group) as follows: sham treatment (group 1); ischemia-reperfusion (group 2); ischemic preconditioning followed by ischemia-reperfusion (group 3); antithrombin + ischemia-reperfusion, similar to group 2 but including antithrombin administration (group 4); and antithrombin + ischemic preconditioning, similar to group 3 but including antithrombin administration (group 5). Blood samples and liver specimens were obtained for measurement of cytokines, myeloperoxidase, and malondialdehyde.