Publications by authors named "K Korpinen"
Personalized multifactorial risk assessment in neoadjuvant-treated breast carcinoma.
Breast Cancer Res Treat
December 2024
Article Synopsis
- The study aims to improve predictions of disease outcomes for breast cancer patients undergoing neoadjuvant treatment (NAT) by analyzing clinical and histopathological data.
- Researchers evaluated a cohort of 257 Finnish breast cancer patients over 13 years, identifying significant prognostic factors and previously overlooked histological features that correlate with treatment response and survival.
- The findings suggest the importance of re-assessing biomarkers post-treatment and developing personalized surveillance and treatment strategies based on comprehensive evaluations of patient data and risk factors.
Purpose: Triple-negative breast cancer (TNBC) is an aggressive disease lacking specific biomarkers to guide treatment decisions. We evaluated the combined prognostic impact of clinical features and novel biomarkers of cell cycle-progression in age-dependent subgroups of TNBC patients.
Methods: One hundred forty seven TNBC patients with complete clinical data and up to 18 year follow-up were collected from Turku University Hospital, Finland.