Publications by authors named "K Kohagura"
Rationale: Although the mortality of severe coronavirus disease 2019 (COVID-19) has decreased after the emergence of the Omicron variant, it remains high in patients on hemodialysis (HD). Remdesivir (RDV) is considered as the first line drug for hospitalized COVID-19 patients, however the evidence regarding the usage in HD patients is lacking because clinical trials of RDV have excluded HD patients for safety reasons. Thus, accumulation of knowledge on the regimen, efficacy, and tolerability of RDV in HD patients is important.
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- Hypertension and aging lead to vascular changes in the kidneys, known as nephrosclerosis, which can contribute to chronic kidney disease (CKD) but aren't always directly linked to renal decline.
- Afferent arteriolopathy, characterized by thickening of blood vessel walls, disrupts kidney blood flow and can cause glomerular hypertension and ischemia, worsening kidney damage over time.
- Recent studies suggest that combining two types of medications—renin-angiotensin system inhibitors (RASis) and sodium-glucose transporter 2 inhibitors (SGLT2is)—is more effective than RASis alone for slowing kidney function decline, highlighting the importance of blood pressure management in CKD treatment.
Green nail syndrome is an infectious nail disorder caused most commonly by . We report a rare case of peritoneal dialysis (PD) exit site infection (ESI) accompanied by -associated green nail syndrome. The patient was treated with oral and topical antibiotics without the need for PD catheter removal.
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- The study investigates how smoking and high uric acid levels (hyperuricemia) impact kidney damage in patients with IgA nephropathy.
- The results show that patients who smoke and have hyperuricemia exhibit the most severe kidney damage, particularly in terms of arteriolar wall thickening.
- The findings suggest that smoking's negative effects on kidney health seem to be significant primarily in those with hyperuricemia, highlighting the need for further studies on their combined impact on kidney function.