Publications by authors named "K Koga"
The cloud point temperatures of aqueous poly(-isopropylacrylamide) (PNIPAM) and poly(ethylene) oxide (PEO) solutions were measured from pH 1.0 to pH 13.0 at a constant ionic strength of 100 mM.
View Article and Find Full Text PDFStudy Question: Does one-step warming (OW), a simplified embryo warming protocol, adversely affect survival and developmental potential in vitrified cleavage or blastocyst stage embryos compared to standard multi-step warming (SW)?
Summary Answer: OW showed no detrimental effects on survival and developmental potential compared to SW in cleavage and blastocyst stage embryos.
What Is Known Already: While standard embryo warming protocols involve a multi-step procedure using a stepwise osmotic solution to avoid a rapid influx of water into the embryo, recent studies suggest that eliminating the stepwise warming process does not reduce embryo survival and embryo transfer outcomes. However, previous reports have focused primarily on pregnancy rates, and a more detailed analysis of the effects of rapid osmotic pressure changes on embryos is necessary to standardize the protocol.
ZnO nanorods have attracted much attention owing to their outstanding properties for chemical gas sensors. Although they show greater sensing properties than conventional nanoparticulate ZnO, high operation temperature (>250-350 °C) is required for them to work even if precious metals are deposited on them to sensitize their sensing properties. Light irradiation is one solution for overcoming the high operation temperature and the gas selectivity because it assists the oxidation activity on the surface that affects the sensor response.
View Article and Find Full Text PDFIntroduction: Anticentromere autoantibodies are associated with refractory IVF/ET failure, but causality is unclear. Experimental models are needed.
Methods: Immature oocytes collected from 23-day-old mice were matured in vitro for 18 h in a culture medium containing an anti-human centromere protein A (CENP-A) polyclonal antibody, and those oocytes' maturity and chromosome/spindle structure were assessed.
Article Synopsis
- - Alport syndrome is a genetic disorder that leads to kidney failure, hearing loss, and eye problems, caused by mutations in type IV collagen genes.
- - Early diagnosis is challenging since renal biopsies often appear normal initially, leading to misdiagnosis as another kidney disease.
- - The study highlights two families misdiagnosed through biopsies but correctly identified via genetic testing, showing that early genetic diagnosis can prevent unnecessary procedures and enhance kidney health outcomes.