Competition between Bipolar Conduction Modes in Extrinsically -Doped MoS: Interaction with Gate Dielectric Matters.

With reduced dimensionality and a high surface area-to-volume ratio, two-dimensional (2D) semiconductors exhibit intriguing electronic properties that are exceptionally sensitive to surrounding environments, including directly interfacing gate dielectrics. These influences are tightly correlated to their inherent behavior, making it critical to examine when extrinsic charge carriers are intentionally introduced to the channel for complementary functionality. This study explores the physical origin of the competitive transition between intrinsic and extrinsic charge carrier conduction in extrinsically -doped MoS, highlighting the central role of interactions of the channel with amorphous gate dielectrics.

Modification of Fc-fusion protein structures to enhance efficacy of cancer vaccine in plant expression system.

Epithelial cell adhesion molecule (EpCAM) fused to IgG, IgA and IgM Fc domains was expressed to create IgG, IgA and IgM-like structures as anti-cancer vaccines in Nicotiana tabacum. High-mannose glycan structures were generated by adding a C-terminal endoplasmic reticulum (ER) retention motif (KDEL) to the Fc domain (FcK) to produce EpCAM-Fc and EpCAM-FcK proteins in transgenic plants via Agrobacterium-mediated transformation. Cross-fertilization of EpCAM-Fc (FcK) transgenic plants with Joining chain (J-chain, J and JK) transgenic plants led to stable expression of large quaternary EpCAM-IgA Fc (EpCAM-A) and IgM-like (EpCAM-M) proteins.

Edge Chipping Resistance and Flexural Strength of CAD-CAM Ceramics Before and After Thermomechanical Aging.

Objectives: To evaluate the complementary mechanical properties of dental ceramics using edge chipping resistance (Rea) and flexural strength before and after thermomechanical aging.

Material And Methods: Computer-aided design and computer-aided manufacturing of ceramic materials, including zirconia (ZR), lithium disilicate (LS2), and resin nanoceramics (RNC), were evaluated. Specimens for flexural strength testing were fabricated with dimensions of 3 × 4 × 25 mm, with 30 specimens per group.

Effect of colistin-tigecycline combination on colistin-resistant and carbapenem-resistant and .

Unlabelled: There is a critical need for treatment strategies to combat carbapenem-resistant Gram-negative pathogens. This study investigates the efficacy of combining low concentrations of colistin with tigecycline against colistin- and carbapenem-resistant and strains. We used two strains of KPC-2-producing and OXA-23-producing , both of which are highly colistin-resistant.

The Immunoregulatory Architecture of the Adult Oral Cavity.

The oral cavity is a critical barrier with immunosurveillance capabilities. A detailed understanding of its cellular, molecular, and spatial architecture is essential for advancing precision medicine across aerodigestive tissues. Here, we present the first integrated atlas of human adult oral and craniofacial tissues, derived from single-cell RNA sequencing of ~250,000 cells from 70 samples across 13 niches, including salivary glands and oral mucosae.