Heat-Killed Enhances Positive Mood States: A Randomized, Double-Blind, Placebo-Controlled Study.

When mood states are impaired, daily life is severely disrupted. To maintain a specific mood state, both positive and negative moods must be controlled; however, methods to maintain a positive mood have not been fully established. Previous studies have suggested that heat-killed MCC1848 has the potential to improve positive moods.

Heat-killed improves mood states: a randomised, double-blind, placebo-controlled study.

We investigated the effects of heat-killed MCC1848 on daily mood states in healthy young adults. Participants (n=58) were randomised to receive heat-killed MCC1848 powder or placebo powder for 4 weeks. During the study period, adverse events were recorded in the participant diary.

Hepatic Steatosis and High-Normal Fasting Glucose as Risk Factors for Incident Prediabetes.

Context: The role of hepatic steatosis (HS) in the initial stages of developing type 2 diabetes remains unclear.

Objective: We aimed to clarify the impact of HS indexed by Fatty Liver Index (FLI) and high-normal fasting plasma glucose (FPG) as risk factors for incident prediabetes in a nonobese cohort.

Methods: Data from 1125 participants with ADA-defined normal glucose metabolism (median age 52 years; BMI 23.

A case of giant enteric muco-submucosal elongated polyp detected by melena.

A 78-year-old woman was admitted for examination and treatment of melena. Although upper and lower gastrointestinal endoscopy and abdominal computed tomography showed no bleeding lesions, oral double-balloon endoscopy revealed a long, slender polyp covered with normal mucosa and accompanied with erosions in the proximal jejunum. Surgical resection was successful.