Publications by authors named "K Kivinummi"

Article Synopsis
  • * In a study involving 264 plasma samples from 63 EOC patients, ctDNA was found in 93% of samples at diagnosis and 100% at disease progression, indicating its effectiveness for monitoring.
  • * Positive ctDNA results after treatment correlated with faster disease progression and lower survival rates, and in some cases, ctDNA detected recurrence earlier than traditional methods by an average of 5.9 months.
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Long noncoding RNAs (lncRNAs) play pivotal roles in cancer development and progression, and some function in a highly cancer-specific manner. However, whether the cause of their expression is an outcome of a specific regulatory mechanism or nonspecific transcription induced by genome reorganization in cancer remains largely unknown. Here, we investigated a group of lncRNAs that we previously identified to be aberrantly expressed in prostate cancer (PC), called TPCATs.

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Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is to provide high-quality evidence on prostate cancer management by unlocking the potential of big data. The project has identified critical evidence gaps in prostate cancer care, via a detailed prioritization exercise including all key stakeholders.

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