Publications by authors named "K Kikuya"

Article Synopsis
  • The study focuses on the ovine HSD17B3 gene, which plays a crucial role in converting androstenedione into testosterone, impacting sex steroid regulation.
  • It highlights that mutations in the HSD17B3 gene are linked to disorders of sex differentiation (DSD) across multiple mammalian species, making its molecular characteristics important to understand.
  • The findings show that while ovine HSD17B3 has some amino acid variations compared to other mammals, these do not significantly affect its enzyme activity, although certain mutations related to DSD do diminish activity, offering insights for further research in this area.
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Aberrant right hepatic arteries are sometimes involved in pancreatic head tumors or accidentally damaged during surgical procedures, which could result in postoperative complications. The risk of such injury has been discussed in patients undergoing pancreatoduodenectomy; however, no reports describe the influence of this anomaly in distal pancreatectomy. We report a patient with pancreatic body cancer with an accessory right hepatic artery following a very unique route.

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The aim of this study is to develop a model predictive controller (MPC) accompanied with a metabolic reaction model controller for controlling ethanol and n-pentanol concentrations and the mole fraction of monomer units in the production of poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate), P(HB-co-HV), a biodegradable copolyester. The controller consists of two parts: one is for alcohol concentration control and the other one is for mole fraction control, and is based on the concept of metabolic flux distribution control. For control of alcohol concentration, conventional proportional and integral (PI) controller and feedforward/feedback controller did not function sufficiently because the large sampling interval of the biosensor led to a severe overshoot of concentration.

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