[Consciousness during anesthesia for cesarean section].

47 women on which sectio cesarean has been done in occasion of belvic-fetal disproportion, anatomical abnormalities of the pelvis, bad position of presentation. We studies presence of consciousnes spontaneous realtion to pain and possibility for contact according the method of Tunstall M.E.

[The multiple organ failure syndrome--its pathophysiology and treatment].

Polyorganic deficiency syndrome (PODS) is a generalized response to the effect of a variety of agents hardly lending itself to control, becoming manifest with rapid proliferation within the body. The issues discussed include: epidemiology with a special reference to panendothelial trauma to pulmonary and other systems with impairment of oxygen utilization by the cells, microcirculation disorders, mediators, ARDS development, disturbed barrier function of the intestinal mucosa, enhanced glutamine consumption with ensuing villous atrophy. Symptoms presented by various organs, treatment consisting in block of stimulation and block of mediators, as well as selective decontamination and adequate diet are also dealt with.

[Resistance to its own antibiotic nigericin and macromolecular synthesis in Streptomyces hygroscopicus 155].

The influence of nigericin (nandavir) on the organism producing it (Streptomyces hygroscopicus 155) was studied with respect to the synthesis of protein, RNA and DNA. The resistance of the mycelium of different ages to the exogenic antibiotic was investigated. Exogenic nigericin had a more marked inhibitory effect on the macromolecular synthesis in a nonproductive variant of the strain.

[Effect of calcium ions on the differentiation of actinomycetes].

The influence of Ca2+ on the formation of the aerial mycelium in 23 actinomycete strains was studied. It was shown that in concentrations up to 5 mM exogenous Ca2+ induced the formation of the aerial mycelium in 11 out of the 23 actinomycete strains tested. The Ca2+ channel blockers (verapamil and nifedipine), calmodulin inhibitor (chlorpromazine) and Ca2+ chelator (EGTA) inhibited the aerial mycelium formation in 3 streptomycete strains out of the 23 actinomycetes.

[Preparation and regeneration of protoplasts of the strain Streptomyces hygroscopicus 155].

Protoplasts of Streptomyces hygroscopicus 155 producing nigericin, a polyether antibiotic, were prepared. Conditions for protoplasting and optimal concentrations of lysozyme and glycine, and the age of mycelium were studied. With the method of the experiment design, concentrations of four components: CaCl2, MgCl2, KH2PO4 and TES buffer in the regeneration medium were determined.