Publications by authors named "K Khadheejath Shabana"
A tetragonal zirconia-faujasitic SAPO-37 zeolite composite (SAP-37ZR) was synergistically stabilised at 550 °C using a temperature programmed reduction method. The presence of the zeolite-ZrO composite phase was confirmed through powder XRD reflection, SEM and TEM-ED pattern analyses. The developed SAP-37ZR composite, exhibiting moderate acidity, was found to be highly active for the production of ethyl levulinate (EL) from furfuryl alcohol with a 99% yield.
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- - This systematic review evaluated how effective and safe tumor necrosis factor (TNF) inhibitors are for treating systemic juvenile idiopathic arthritis (JIA) by examining various studies from 2000 to 2021.
- - The review included one randomized controlled trial (RCT) and 22 observational studies, with the RCT showing that infliximab had moderate efficacy (ACR Pediatric responses of about 63.8% at 14 weeks) but also reported significant side effects like anaphylaxis in 17% of patients.
- - The findings suggest that while TNF inhibitors appear relatively safe, they are not very effective for systemic JIA, indicating a need for more rigorous research to better evaluate their use in these
Objectives: This systematic review assessed the efficacy and safety of abatacept in patients with systemic juvenile idiopathic arthritis (JIA).
Methods: Studies published between 2000 and 2021 were searched using PubMed, Embase, Cochrane, Ichushi-Web, and clinical trial registries. The risk of bias was assessed according to the manual for development clinical practice guidelines by Minds, a project to promote evidence-based medicine in Japan.
Background: Thiazolidine-2,4-dione (2,4-TZD) is a flexible pharmacophore and a privileged platform and contains a five-membered ring with a 2-oxygen atom with double bond 2,4- position and one nitrogen atom as well as sulphur containing in the heterocyclic compound. A famous electron-rich nitrogen transporter combines invigorating electronic properties with the prospective for elemental applications. Thiazolidine-2,4-dione analogues have been synthesized using a variety of methods, all of which have shown to have a strong biological effect.
View Article and Find Full Text PDFBackground: Piperine is a natural compound found in black pepper that has been traditionally used for various therapeutic purposes. In the ayurvedic system of medication there is a lot of evidence which shows that the piperine is widely used for different therapeutic purpose. In recent years, there has been an increasing interest in the pharmacological and therapeutic potential of piperine and its derivatives in modern medicine.
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