Publications by authors named "K Kenneth Caswell"
Article Synopsis
- Traumatic brain injury (TBI) is common in veterans and is linked to various long-term sleep-wake disorders (SWD) that are not fully understood, which complicates diagnosis and treatment.
- A literature review identified gaps in knowledge regarding the pathophysiology of TBI-related sleep issues, compared them with post-traumatic stress disorder sleep disturbances, and highlighted the importance of biomarkers and treatment strategies.
- The conclusion stresses that a better understanding of the scientific basis for TBI and its impact on sleep is needed, focusing on biomarkers and neuroimaging to improve diagnosis and therapy in affected veterans.
Background: Li-Fraumeni syndrome (LFS) is a penetrant cancer predisposition syndrome (CPS) associated with the development of many tumor types in young people including osteosarcoma and breast cancer (BC). The McGill Interactive Pediatric OncoGenetic Guidelines (MIPOGG) decision-support tool provides a standardized approach to identify patients at risk of CPSs.
Methods: We conducted a cost-utility analysis, from the healthcare payer perspective, to compare MIPOGG-guided, physician-guided, and universal genetic testing strategies to detect LFS in female patients diagnosed at an age of less than 18 years with osteosarcoma.
Background: Cancer predisposition syndromes (CPSs) are responsible for at least 10% of cancer diagnoses in children and adolescents, most of which are not clinically recognised prior to cancer diagnosis. A variety of clinical screening guidelines are used in healthcare settings to help clinicians detect patients who have a higher likelihood of having a CPS. The McGill Interactive Pediatric OncoGenetic Guidelines (MIPOGG) is an electronic health decision support tool that uses algorithms to help clinicians determine if a child/adolescent diagnosed with cancer should be referred to genetics for a CPS evaluation.
View Article and Find Full Text PDFPurpose: This single-arm, decentralized pilot study assessed patient journey, positive airway pressure (PAP) usage and program satisfaction for users of an entirely virtual telemedicine program for obstructive sleep apnea (OSA) diagnosis and management. This analysis focuses specifically on the subset of participants in the program who were diagnosed with OSA and prescribed PAP therapy.
Methods: The Verily Clinical Studies Platform was used for virtual screening, consent, and enrolling eligible patients from North Carolina and Texas.
Objective: Patient and family liaison practitioners are a relatively recent addition to UK helicopter emergency medical services to support patients with their recovery. A service evaluation was completed that mapped the current provision of patient and family liaison practitioner roles in helicopter emergency medical services in the United Kingdom.
Methods: An online survey was distributed to key stakeholders involved with UK helicopter emergency medical service patient and family liaison practitioner roles.