Publications by authors named "K Kelsey"
Introduction: The relations between coffee and tea consumption and head and neck cancer (HNC) incidence are unclear. With increasing global HNC burden, this study aims to examine the association between coffee, tea, and HNC.
Methods: A pooled analysis of 9548 HNC cases and 15,783 controls from 14 individual-level case-control studies was conducted from the International Head and Neck Cancer Epidemiology consortium.
The aim of this study is to investigate the prognostic role of body mass index (BMI) on survival from head and neck cancer (HNC). We performed a pooled analysis of studies included in the International Head and Neck Cancer Epidemiology consortium. We used Cox proportional hazards models to estimate the adjusted hazard ratios (HR) for overall survival and HNC-specific survival, and we stratified the results according to cancer site.
View Article and Find Full Text PDFBlack adults have higher incidence of all-cause mortality and worse cardiovascular disease (CVD) outcomes when compared to other U.S. populations.
View Article and Find Full Text PDFBackground: Cardiometabolic risk factors among youth are rising. Epigenetic age acceleration, a biomarker for aging and disease-risk, has been associated with adiposity in children, but its association with other cardiometabolic risk markers remains understudied. We employed data from the Health Outcomes and Measures of the Environment (HOME) study, a prospective pregnancy and birth cohort in the greater Cincinnati metropolitan area, to examine whether accelerated epigenetic age at birth as well as accelerated epigenetic age and faster pace of biological aging at age 12 years were associated with higher cardiometabolic risk in adolescents.
View Article and Find Full Text PDFArticle Synopsis
- This study explores blood biomarkers that can predict responses to immune checkpoint inhibitors (ICIs) for patients with recurrent/metastatic head and neck squamous cell carcinoma, addressing challenges like tumor sample variability.
- Researchers enrolled 100 patients and analyzed blood immune profiles, focusing on factors like tumor mutational burden (TMB) and PD-L1 scores, with a goal to find associations with treatment outcomes.
- Key findings revealed that high levels of neutrophils and monocytes were linked to worse survival, while higher CD4T cells correlated with better outcomes, highlighting the potential of using blood tests for predicting ICI treatment responses.