Publications by authors named "K Kawahira"
Article Synopsis
- Sulforaphane (SFaN) is a compound from food known for its health benefits, particularly in treating atherosclerosis, diabetes, and obesity, but how it works isn't fully understood.
- Researchers identified SFaN-binding proteins and discovered that SFaN interacts with acyl protein thioesterase 2 (APT2).
- SFaN binds to APT2 through a specific residue (C56), inhibiting the palmitoylation process of APT2 and affecting its location within the plasma membrane, highlighting a new role for SFaN in regulating APT2 activity.
Immunity is known to persist after vaccination for varicella zoster virus, but the duration of immunity in patients who develop herpes zoster (HZ) remains unknown. To investigate the association between a past history of HZ and its occurrence in the general population. The Shozu HZ (SHEZ) cohort study included data for 12 299 individuals aged ≥50 years with information on their HZ history.
View Article and Find Full Text PDFPurpose: Pure motor isolated hand palsy (PMIHP) following infarction of the "hand knob" area is a rare entity in stroke. PMIHP usually recovers within the first few days, but there are rare cases where patients do not recover rapidly. Herein, we report a case of residual PMIHP in which repetitive facilitative exercise under concurrent low-amplitude continuous neuromuscular electrical stimulation ("RFE-under-cNMES") was introduced to improve hand function.
View Article and Find Full Text PDFStudy Design: An open-label, randomized, controlled, observer-blinded trial.
Introduction: Repetitive facilitative exercise (RFE) is a movement therapy to recover from hemiparesis after stroke. However, improvement is inhibited by spasticity.
Background: The impact of body mass index on incidence of herpes zoster is unclear. This study investigated whether body mass index was associated with a history of herpes zoster and incidence during a 3-year follow-up, using data from a prospective cohort study in Japan.
Methods: In total, 12,311 individuals were included in the cross-sectional analysis at baseline, of whom 1,818 with a history of herpes zoster were excluded from the incidence analysis, leaving 10,493 individuals.