Nihon Ronen Igakkai Zasshi
September 2024
Objective: To evaluate the frequency of malnutrition and sarcopenic obesity in elderly patients with diabetes according to the Global Leadership Initiative on Malnutrition (GLIM) phenotypes.
Methods: The subjects were outpatients with diabetes who were ≥65 years of age and were managed at Ise Red Cross Hospital. Undernutrition was assessed and categorized into the following GLIM criteria phenotypes: (1) no undernutrition, (2) undernutrition (weight loss or low body mass index [BMI]/no low appendicular skeletal muscle mass index [ASMI]), (3) undernutrition (no weight loss or no low BMI/low ASMI), and (4) undernutrition (weight loss or low BMI/low ASMI).
A 64-year-old woman presented with agranulocytosis, anemia, and bacteremia, leading to a diagnosis of T-cell large granular lymphocytic leukemia (T-LGLL). A molecular analysis identified a signal transducer and activator of transcription 3 (STAT3) Y640F variant. Initial treatment with cyclophosphamide and prednisolone did not improve her condition, but serious infections were observed.
View Article and Find Full Text PDF